Calcium, extracellular

A mineral essential for bones, muscle, and nerve signalling.

Last reviewedJune 16, 2026
Serum
sample type
~5 mL
blood needed
~7 days
results in app
Any time of day
best timing
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In short

Calcium is the most abundant mineral in the body. Most of it is stored in bones and teeth, but a small, tightly controlled amount circulates in the blood, where it is essential for nerve signalling, muscle contraction, blood clotting and heart rhythm.

This test measures total calcium in serum. The value reflects calcium in the extracellular fluid, the compartment outside your cells that includes blood, which is the standard sample used to assess calcium status.

Electrolytes & Hydration
Reviewed against DGKL reference practice.
Why it matters

Why test this?

The body keeps blood calcium within a narrow range using parathyroid hormone, vitamin D and the kidneys. Measuring it shows whether that balance is holding.

A high level can point to overactive parathyroid glands, certain cancers or too much vitamin D. A low level can signal low parathyroid activity, vitamin D deficiency or kidney problems, and may cause cramps or tingling.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

MeasureAdult range (SI)
Total calcium, serum2.20 to 2.60 mmol/L

Ranges are guidance and vary by lab. Calcium results are best corrected for albumin. Cite your laboratory's reference interval.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • Whether your blood calcium sits within the healthy range.
  • Early signals of parathyroid, vitamin D or kidney issues.
  • Context for bone health when read with other markers.
What affects your level

What can affect this result?

What can skew the result

Low albumin lowers total calcium without changing the active free fraction, so albumin correction matters. Prolonged tourniquet application, high vitamin D intake, thiazide diuretics and lithium can shift results. Haemolysis can interfere.

Best interpreted with

Read with albumin (for corrected calcium), phosphate, parathyroid hormone (PTH) and vitamin D.

How testing works

How is this tested?

Sample
Serum
Blood needed
~5 mL
Method
Photometry
Best timing
Any time of day
FAQ

Common questions

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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