The ratio of hs-CRP to HDL, a combined inflammation and heart-risk marker.
The hs-CRP to HDL ratio is a calculated value, not a separate blood test. It combines high-sensitivity CRP, a marker of low-grade inflammation, with HDL cholesterol, the protective cholesterol that also has anti-inflammatory effects.
The formula is: hs-CRP ÷ HDL cholesterol, using the units reported by the lab.
Inflammation and low HDL both contribute to cardiovascular risk. Combining them aims to capture both in one number, and the ratio has been studied as a marker of inflammatory and metabolic risk.
A higher ratio reflects more inflammation relative to protective cholesterol and has been linked with greater cardiometabolic risk. A lower ratio is more favourable.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
There is no firmly established healthy reference range for the hs-CRP to HDL ratio. It is used in research as a relative risk marker, where higher values suggest greater inflammatory and metabolic risk. Interpret as a trend with a clinician rather than against a fixed cutoff.
CRP rises with any infection, injury or recent illness and is non-specific, so it should be measured when you are well. HDL can be affected by alcohol, smoking and some medications. Recent illness can raise CRP and inflate the ratio for reasons unrelated to cardiovascular risk.
Read with its components, hs-CRP and HDL cholesterol, and alongside the full lipid panel and other cardiovascular risk factors.
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