PDW-SD

A measure of variation in platelet size.

Last reviewedJune 16, 2026
Whole blood
sample type
~3 mL
blood needed
~7 days
results in app
Any time of day
best timing
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In short

PDW-SD, platelet distribution width by standard deviation, measures how much platelet size varies in your blood. A wider value means the platelets differ more in size, a narrower value means they are more uniform.

It is one of the platelet indices reported automatically by haematology analysers during a complete blood count. It is read together with the platelet count and mean platelet volume.

Blood Health (CBC & Iron)
Reviewed against DGKL reference practice.
Why it matters

Why test this?

Platelet size variation can reflect how actively the bone marrow is producing platelets. A high PDW often goes with newly released, larger platelets, which can occur when platelets are being used up or replaced quickly.

On its own PDW is not diagnostic, but combined with other platelet indices it can support the picture of platelet activation, bone marrow response, or certain inflammatory states.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Typical adult guidance, strongly analyser dependent:

ResultRange
PDW-SD9 to 17 fL

This index has no single agreed reference range and differs between analyser models. Always read your result against your laboratory's interval.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • How much your platelets vary in size.
  • A supporting clue about platelet production and turnover.
  • Context for your platelet count and mean platelet volume.
What affects your level

What can affect this result?

What can skew the result

Platelet clumping, delayed analysis, and EDTA-related platelet changes can distort the result. Values are not comparable between different analyser brands. PDW is rarely used alone to make decisions.

Best interpreted with

Read alongside platelet count, mean platelet volume, plateletcrit, and the platelet large cell ratio.

How testing works

How is this tested?

Sample
Whole blood
Blood needed
~3 mL
Method
Flow cytometry
Best timing
Any time of day
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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