Platelet large cell ratio (P-LCR), %

The proportion of large platelets, a marker of platelet production.

Last reviewedJune 16, 2026
Whole blood
sample type
~3 mL
blood needed
~7 days
results in app
Any time of day
best timing
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In short

Platelet large cell ratio, or P-LCR, is the proportion of your platelets that are larger than a set size threshold, usually 12 femtolitres. It is reported as a percentage by haematology analysers.

Larger platelets tend to be younger and more active, so P-LCR gives an idea of how many big, freshly produced platelets are circulating.

Blood Health (CBC & Iron)
Reviewed against DGKL reference practice.
Why it matters

Why test this?

A higher proportion of large platelets can mean the bone marrow is releasing new platelets quickly, which happens when platelets are being used up or destroyed. It tends to move together with mean platelet volume.

P-LCR is not a standalone diagnostic test, but together with the other platelet indices it can support the picture of platelet turnover and activation.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Typical adult guidance, analyser dependent:

ResultRange
Platelet large cell ratio (P-LCR)15 to 35 %

This index has no single agreed range and differs between analyser models. Read your result against your laboratory's interval.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • The share of your platelets that are large and likely young.
  • A supporting clue about how fast platelets are being produced.
  • Context for mean platelet volume and the platelet count.
What affects your level

What can affect this result?

What can skew the result

Platelet clumping, delay before analysis, and EDTA-related size changes can distort the value. It is not comparable between analyser brands and is not used alone to make decisions.

Best interpreted with

Read alongside mean platelet volume, platelet count, and platelet distribution width.

How testing works

How is this tested?

Sample
Whole blood
Blood needed
~3 mL
Method
Flow cytometry
Best timing
Any time of day
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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