Sodium, extracellular

A key electrolyte that regulates fluid balance and nerve function.

Last reviewedJune 16, 2026
Serum
sample type
~5 mL
blood needed
~7 days
results in app
Any time of day
best timing
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In short

Sodium is the main electrolyte in the fluid outside your cells. It controls the body's water balance, blood volume and blood pressure, and supports nerve and muscle function.

This test measures sodium in serum or plasma. The value reflects sodium in the extracellular fluid, the compartment outside your cells, which is the standard measurement used to assess sodium and water balance.

Electrolytes & Hydration
Reviewed against DGKL reference practice.
Why it matters

Why test this?

Sodium and water move together, so the blood sodium level is largely a measure of how concentrated or diluted your body fluids are. The kidneys and hormones such as ADH and aldosterone keep it stable.

A high level usually reflects water loss or dehydration. A low level is common and can come from excess water, certain medications, heart, liver or kidney conditions, and may cause confusion or headaches.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

MeasureAdult range (SI)
Sodium, serum135 to 145 mmol/L

Ranges are guidance and vary by lab. Cite your laboratory's reference interval.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • Whether your sodium and water balance is normal.
  • A signal of dehydration or fluid overload.
  • Context for blood pressure, kidney and hormone function.
What affects your level

What can affect this result?

What can skew the result

Very high blood fats or protein can cause a falsely low sodium on some analysers (pseudohyponatraemia). High blood glucose lowers measured sodium. Diuretics, antidepressants and intravenous fluids shift true values. Sample handling errors can interfere.

Best interpreted with

Read with potassium, chloride, bicarbonate, glucose and kidney function (creatinine, eGFR).

How testing works

How is this tested?

Sample
Serum
Blood needed
~5 mL
Method
Ion-selective electrode
Best timing
Any time of day
FAQ

Common questions

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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