Transferrin (Iron) Saturation

The percentage of iron-binding capacity that is filled, a core iron marker.

Last reviewedJune 16, 2026
Calculated
sample type
Not applicable (calculated)
blood needed
~7 days
results in app
Morning, 7 to 10am, fasting preferred
best timing
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In short

Transferrin saturation, also called iron saturation, shows how much of your iron-carrying protein transferrin is actually loaded with iron. It is a calculated value, not a separate measurement.

The formula is: transferrin saturation (%) = serum iron divided by total iron-binding capacity, multiplied by 100. It tells you the proportion of available transport capacity that is being used.

Blood Health (CBC & Iron)
Reviewed against DGKL reference practice.
Why it matters

Why test this?

Transferrin saturation is one of the best everyday markers of iron supply. A low value points to iron deficiency, while a high value can suggest iron overload, including conditions like haemochromatosis.

Because it combines iron and iron-binding capacity in one ratio, it gives a clearer picture of iron availability than either value alone.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Typical adult guidance:

ResultRange
Transferrin saturation20 to 45 %

Below about 20% suggests low iron supply, above about 45 to 50% can suggest iron overload. Ranges vary by lab; read your result against the local interval.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • How much of your iron transport capacity is in use.
  • A low result that can flag iron deficiency.
  • A high result that can flag iron overload, read together with ferritin.
What affects your level

What can affect this result?

What can skew the result

Serum iron swings through the day and after meals or iron supplements, so a morning, fasting sample is preferred. Recent iron intake can falsely raise the result. Inflammation affects the components differently.

Best interpreted with

Read alongside ferritin, serum iron, and total iron-binding capacity for a full iron status picture.

How testing works

How is this tested?

Sample
Calculated
Blood needed
Not applicable (calculated)
Method
Calculated
Best timing
Morning, 7 to 10am, fasting preferred
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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