Alpha-fetoprotein expressed as multiples of the median, used in screening.
Alpha-fetoprotein in MoM, or multiples of the median, is a way of reporting maternal serum AFP during pregnancy. Instead of a raw value, the result is shown as how far it sits above or below the median for that stage of pregnancy.
This makes results comparable across the weeks of pregnancy and is used within prenatal screening, not as a routine adult tumor marker.
AFP MoM is part of second-trimester screening that estimates the chance of certain conditions in the pregnancy, such as neural tube defects and some chromosomal differences. It is combined with other markers and the gestational age.
A result is a probability adjustment, not a diagnosis. A higher or lower MoM shifts the estimated risk and may lead to further tests such as detailed ultrasound. Results are always interpreted by a doctor within the full screening result.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
AFP MoM is an index, not a fixed cutoff. A value near 1.0 MoM is the median for the gestational age.
| Measure | Note |
|---|---|
| AFP MoM | 1.0 = the median for that gestational week; values are interpreted within the full screen |
Cutoffs depend on the screening program and laboratory. Aligned to German laboratory practice (DGKL).
The result depends heavily on accurate gestational dating, so an error in dates skews the MoM. Multiple pregnancy, maternal weight, diabetes, and ethnicity affect interpretation and are corrected for. It is a screening tool only, not a diagnosis.
Read together with hCG, unconjugated estriol, inhibin A, and the gestational age within a combined screening result.
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