Gamma-Aminobutyric Acid (GABA)

The main calming neurotransmitter, also measured as an amino acid.

Last reviewedJune 16, 2026
Plasma
sample type
~5 mL
blood needed
~7 days
results in app
Morning, fasting
best timing
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In short

Gamma-aminobutyric acid, usually called GABA, is the main calming signal in the nervous system. It is made from glutamic acid and helps balance the excitatory signals in the brain. As an amino acid it can also be measured in blood.

Comprehensive Health Check
Reviewed against DGKL reference practice.
Why it matters

Why test this?

It is measured as part of a plasma amino acid profile. Blood GABA does not directly reflect brain activity, so it is read for context within the wider panel rather than as a test of mood or anxiety. Plasma levels are normally very low.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

GroupAdult fasting plasma range
Adults0 to 5 µmol/L

Plasma GABA is normally very low. Amino acid ranges vary by laboratory and method, and are best read as part of the full plasma amino acid profile.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • Context on GABA within your amino acid profile.
  • Awareness that blood GABA does not directly measure brain function.
  • Help interpreting the rest of your amino acid profile.
What affects your level

What can affect this result?

What can skew the result

Recent protein intake, supplements, fasting state, and time of day affect the result. Blood GABA does not reflect brain levels. A fasting morning sample gives the most reliable reading.

Best interpreted with

Read as part of the full plasma amino acid profile.

How testing works

How is this tested?

Sample
Plasma
Blood needed
~5 mL
Method
Ion-exchange chromatography or LC-MS/MS
Best timing
Morning, fasting
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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