A urea-cycle-related amino acid metabolite.
Homocitrulline is not a protein building block. It forms when the amino acid lysine reacts with carbamoyl phosphate, a urea cycle intermediate. It appears in plasma in small amounts and can rise when the urea cycle is under strain.
Homocitrulline is reported as part of a full amino acid profile, mainly as a clue rather than a routine health marker. A raised level can point toward certain inherited urea cycle disorders, so it is read together with ammonia, ornithine, citrulline and the other amino acids rather than alone.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
Adult fasting plasma, guidance only:
| Analyte | Typical adult range (µmol/L) |
|---|---|
| Homocitrulline | 0 to 5 |
Ranges vary by laboratory and assay and are read as part of the full amino acid profile.
Results are affected by recent diet, recent protein intake, fasting state and the time of day the sample is taken.
Read as part of the full plasma amino acid profile.
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