Hydroxylysine

A modified amino acid that is a building block of collagen.

Last reviewedJune 16, 2026
Plasma
sample type
~5 mL
blood needed
~7 days
results in app
Morning, fasting
best timing
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In short

Hydroxylysine is a modified form of the amino acid lysine, made after lysine is built into collagen, the main structural protein in skin, bone and connective tissue. Free hydroxylysine in plasma comes mostly from collagen turnover.

Comprehensive Health Check
Reviewed against DGKL reference practice.
Why it matters

Why test this?

Hydroxylysine is reported as part of a full amino acid profile. It sits at very low levels in healthy adults. Unusual results are uncommon and usually relate to rare inherited disorders of collagen processing, so it is read in the context of the whole profile.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Adult fasting plasma, guidance only:

AnalyteTypical adult range (µmol/L)
Hydroxylysine0 to 2

Ranges vary by laboratory and assay and are read as part of the full amino acid profile.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • Whether hydroxylysine sits in the usual low adult range.
  • A small additional data point linked to collagen turnover.
  • In rare cases, a clue that supports a closer look at connective tissue metabolism.
What affects your level

What can affect this result?

What can skew the result

Results are affected by recent diet, recent protein intake, fasting state and the time of day the sample is taken.

Best interpreted with

Read as part of the full plasma amino acid profile.

How testing works

How is this tested?

Sample
Plasma
Blood needed
~5 mL
Method
Ion-exchange chromatography or LC-MS/MS
Best timing
Morning, fasting
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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