Proline

An amino acid that is a key building block of collagen.

Last reviewedJune 16, 2026
Plasma
sample type
~5 mL
blood needed
~7 days
results in app
Morning, fasting
best timing
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In short

Proline is a non-essential amino acid your body can make. It is a major building block of collagen, the structural protein in skin, bone and connective tissue, which is why proline is closely linked to tissue strength and repair.

Comprehensive Health Check
Reviewed against DGKL reference practice.
Why it matters

Why test this?

Plasma proline is part of a full amino acid profile and reflects protein intake and collagen metabolism. Markedly high levels can point toward inherited disorders of proline breakdown, so it is read in the context of the whole profile.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Adult fasting plasma, guidance only:

AnalyteTypical adult range (µmol/L)
Proline112 to 335

Ranges vary by laboratory and assay and are read as part of the full amino acid profile.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • Whether proline sits in the usual adult fasting range.
  • A data point linked to collagen and connective tissue metabolism.
  • In rare cases, a clue that supports a closer look at amino acid breakdown.
What affects your level

What can affect this result?

What can skew the result

Results are affected by recent diet, recent protein intake, fasting state and the time of day the sample is taken.

Best interpreted with

Read as part of the full plasma amino acid profile.

How testing works

How is this tested?

Sample
Plasma
Blood needed
~5 mL
Method
Ion-exchange chromatography or LC-MS/MS
Best timing
Morning, fasting
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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