A gene variant linked to detoxification and cancer-risk pathways.
CYP1A1 is a gene that codes for cytochrome P450 1A1, an enzyme that helps the body break down certain foreign substances. It is active mainly in the lungs and other tissues exposed to the outside world, where it processes compounds found in tobacco smoke, grilled food and air pollution.
This enzyme is part of phase one detoxification. It chemically changes substances so the body can clear them, though some of these intermediate products can be more reactive than the original.
Common variants in CYP1A1, such as the m1 variant (rs4646903), can change how quickly the enzyme works. Studying these variants helps researchers understand why some people process environmental chemicals differently and why exposure to smoke or pollutants may carry different risks depending on a person's genetics.
A variant here is a predisposition, not a diagnosis. It is most meaningful when read alongside lifestyle factors such as smoking, diet and air quality.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
This test reports a genotype, not a numeric value. Results are given as the combination of alleles you carry.
| Genotype | General effect |
|---|---|
| Common (wild type) | Typical enzyme activity |
| One variant allele | Altered activity, predisposition only |
| Two variant alleles | More pronounced shift in activity |
Interpretation depends on the specific variant tested and should be read with lifestyle factors. Genetics are a predisposition, not a diagnosis.
Genetics are stable and do not change over time, so the result is reliable lifelong. A variant signals a predisposition, not a diagnosis, and does not on its own mean disease will occur.
Best read alongside other detoxification gene variants such as SULT1A1, and in the context of smoking history and environmental exposures.
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