A gene variant affecting detoxification and hormone processing.
SULT1A1 is a gene that codes for a sulfotransferase enzyme. It attaches a sulfate group to many compounds, which is a key step in phase two detoxification. This helps the body process hormones such as estrogen, certain drugs and dietary compounds, and prepare them for removal.
The enzyme is active in the liver and gut, and common variants change how fast it works.
The variant SULT1A1*2 (rs9282861) lowers enzyme activity and stability. Looking at this gene gives context for how efficiently you process hormones and some dietary and environmental compounds. It is studied in relation to estrogen handling and detoxification capacity.
A variant here is a predisposition, not a diagnosis.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
This test reports a genotype, not a numeric value. Results are given as the alleles you carry, commonly at rs9282861 (SULT1A1*2).
| Genotype | General effect |
|---|---|
| Common (wild type) | Typical sulfation activity |
| One variant allele | Reduced activity |
| Two variant alleles | Lowest activity and stability |
Interpretation is general guidance. Genetics are a predisposition, not a diagnosis.
Genetics are stable and do not change over time. The result is a predisposition for sulfation capacity, not a diagnosis. Diet and medications also affect this pathway.
Best read alongside other detoxification gene variants such as CYP1A1, and in the context of hormone-related markers where relevant.
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