Isoleucine

An essential branched-chain amino acid that supports muscle and energy.

Last reviewedJune 16, 2026
Plasma
sample type
~5 mL
blood needed
~7 days
results in app
Morning, fasting
best timing
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In short

Isoleucine is an essential amino acid and one of the three branched-chain amino acids, alongside leucine and valine. Your body cannot make it, so it comes from protein in food. It supports muscle protein, energy production and blood sugar handling.

Comprehensive Health Check
Reviewed against DGKL reference practice.
Why it matters

Why test this?

Plasma isoleucine is part of a full amino acid profile and reflects protein intake and how your body handles the branched-chain amino acids. Low levels can reflect poor intake, while high levels are seen in some inherited metabolic conditions such as maple syrup urine disease. It is most useful read with leucine and valine.

Reference ranges

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Adult fasting plasma, guidance only:

AnalyteTypical adult range (µmol/L)
Isoleucine37 to 94

Ranges vary by laboratory and assay and are read as part of the full amino acid profile.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.
What you'll learn

What insights will this test give you?

  • Whether isoleucine sits in the usual adult fasting range.
  • How it compares with the other branched-chain amino acids, leucine and valine.
  • A piece of the picture of how your body handles dietary protein.
What affects your level

What can affect this result?

What can skew the result

Results are affected by recent diet, recent protein intake, fasting state and the time of day the sample is taken.

Best interpreted with

Read as part of the full plasma amino acid profile.

How testing works

How is this tested?

Sample
Plasma
Blood needed
~5 mL
Method
Ion-exchange chromatography or LC-MS/MS
Best timing
Morning, fasting
FAQ

Common questions

Related biomarkers

Markers usually read alongside this one

On this page
Why testReference rangesWhat you'll learnWhat affects itHow testing worksSourcesFAQ
✦ Privately insured? German PKV usually reimburses.

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